C4zip -

Produced by Millipore , C4 Zip-tips are 10 µL pipette tips containing a specialized C4 (butyl) stationary phase resin. Unlike the more common C18 tips used for peptides, the C4 resin is optimized for larger, more hydrophobic molecules like intact proteins and large polypeptides. Why C4 over C18?

Aspirating and dispensing the protein sample multiple times to maximize binding. Produced by Millipore , C4 Zip-tips are 10

Using these tips typically follows a simple four-step process: Produced by Millipore

Essential when working with low-abundance samples. Produced by Millipore , C4 Zip-tips are 10

Preparing the resin with a wetting solution (e.g., 50:50 acetonitrile in water).

Rinsing with a buffer like 0.1% trifluoroacetic acid (TFA).

Perfect for recovering larger proteins without losing them to the resin.