The development of PE is governed by , which consists of venous stasis, endothelial injury, and a hypercoagulable state.
: For high-risk (hemodynamically unstable) patients, systemic thrombolysis (e.g., Alteplase) is recommended to rapidly dissolve the clot.
Diagnosis is often challenging because symptoms like dyspnea and chest pain are non-specific. Download Embolie pulmonaire aiguГ« pdf
Acute Pulmonary Embolism (PE) is a critical cardiovascular emergency characterized by the sudden obstruction of a pulmonary artery, typically by a blood clot originating from deep vein thrombosis (DVT) in the lower limbs. As a leading cause of in-hospital mortality, its management requires rapid risk stratification and adherence to standardized clinical guidelines. Pathophysiology and Etiology
: Obstruction causes a ventilation-to-perfusion ( ) mismatch, leading to hypoxemia and respiratory distress. Diagnostic Framework The development of PE is governed by ,
Treatment strategies are dictated by the patient's hemodynamic stability and risk category.
: When thrombolysis is contraindicated or fails, options include catheter-directed thrombectomy or surgical embolectomy. Prognosis and Follow-Up Acute Pulmonary Embolism (PE) is a critical cardiovascular
: Once a clot lodges in the pulmonary vascular bed, it increases pulmonary vascular resistance, which can lead to acute right ventricular (RV) failure and hemodynamic collapse.