Everything Has Changedgrey's Anatomy : Season 1... May 2026

: Revealed to be the nephew of Derek and Amelia Shepherd.

" Everything Has Changed " is the premiere episode of of Grey's Anatomy , representing a major "soft reboot" for the series. This guide covers the key plot points and character shifts from this pivotal transition. Plot Overview

: Bailey initially steps away from her duties, leaving Webber to work on rebuilding the teaching program.

: Already had a prior connection to Link before starting her internship.

: Joins the program after overcoming significant financial and personal hurdles. Major Character Status