Retroviruses are responsible for several significant human diseases. The most well-known is , which attacks the immune system's T-cells and can lead to AIDS . Other notable human retroviruses include:
: Another enzyme, integrase , carries this viral DNA into the cell's nucleus and "clips" it into the host's own DNA. At this stage, the integrated viral DNA is known as a provirus . Retrovirus
: Finally, a protease enzyme cleaves the viral proteins into their functional forms, maturing the virus so it can infect new cells. Human Health and Diseases Retrovirus