On September 15, 2022, Villarreal traveled to Israel for a demanding midweek fixture.
: Álex Baena secured a 1–2 victory for the "Yellow Submarine" with a strike in the 67th minute, assisted by Yéremy Pino. Match 2: A High-Scoring Draw in Spain Villarreal vs Hapoel Be'er
The return leg on October 27, 2022, at the Estadio Ciudad de Valencia, proved even more unpredictable. On September 15, 2022, Villarreal traveled to Israel
: Hapoel's Rotem Hatuel leveled the score in the 63rd minute, temporarily shifting the game's momentum. On September 15