: A monthly chewable tablet that protects against heartworm, fleas, and ticks. It requires a veterinary prescription and can be found at Chewy or Petco .
However, shortly after its release, reports of adverse events began to surface. The most serious was drug-induced pemphigus foliaceus , which causes the immune system to attack skin cells, resulting in painful pustules and crusting. Large breeds, such as Labrador Retrievers, appeared to be at higher risk. Additionally, the amitraz component was linked to neurological side effects like seizures, ataxia (loss of coordination), and profound lethargy. By May 2011, Pfizer ceased all production to prioritize animal safety. Safe Alternatives for Flea and Tick Prevention
ProMeris for dogs was globally in 2011 and is no longer available for purchase from any legitimate retailer. The manufacturer, Pfizer Animal Health (now Zoetis), voluntarily withdrew the product following significant safety concerns, including a link to a severe autoimmune skin disease called pemphigus foliaceus and various neurological events. The Discontinuation of ProMeris: A Cautionary Tale